OFLOXACIN

Product Name : OFLOXACIN

Molecular Formula :C18H20FN3O4

Molecular Weight : 361.37

Synonyms : 7H- Pyrido [1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo( + )

CAS No : 82419-36-1


Sr. No. Test Specifications
1 Description Pale yellowish-white to light yellowish-white crystals or crystalline powder.
2 Solubility Sparingly soluble in chloroform; slightly soluble in alcohol, in methanol and in water.
3 Identification
– By IR

– By UV

The IR absorption spectrum of the test preparation should exhibit maxima at the same wavelength as that of a similar preparation of Ofloxacin working standard.
To comply
4 Residue on ignition (%w/w) Not more than 0.1
5 Arsenic (µg/g) Not more than 1
6 Heavy Metal Not more than 10μ g/g
7 Organic Impurities (By HPLC,% w/w)

Individual Impurity

Total Impurities


Not more than 0.3

Not more than 0.5
8 Residual Solvents (By GCHS,%w/w)
Methanol
Ethanol

Not more than 0.005
Note more than 0.05
9 Optical rotation Between +1° and -1°
10 Loss on drying (%w/w) Not more than 0.20
11 Assay (By Chemical, %w/w)ODB Between 98.5 and 101.5
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